Correlation between BCG Immunization Status and The Incidence of Tuberculosis among Children

Main Article Content

Annisa Nisa
Ulfa Hamdanah
Anita Dwi Ariyani
Corresponding Author:
Annisa Nisa |


Introduction: A children tend to have a high risk on the tuberculosis (TB) infection. BCG immunization is well known as effective way to protect the children from the infection of TB bacteria. Therefore, the study aim was to investigate a correlation between BCG immunization status and the incidence of tuberculosis among children.

Methods: A retrospective case-control study design was used. In total 34 children, whose aged between 1 to 12 years old and visited Wonorejo Primary Health Center between September, 12nd to 16th 2019 recruited as study participant. The Chi-square test was used in this study.

Results: There was a significant correlation between BCG immunization status and the incidence of tuberculosis among children with P value = .008, < .05.

Conclusion: Among five from six children who did not received the BCG immunization were suffered with TB bacteria infection.


Article Details

How to Cite
A. Nisa, U. Hamdanah, and A. D. Ariyani, “Correlation between BCG Immunization Status and The Incidence of Tuberculosis among Children”, Babali Nurs. Res., vol. 1, no. 1, pp. 39-46, Mar. 2020.


[1] H. Gunawan et al., “Various cutaneous tuberculosis with rare clinical manifestations: A case series,” Int. J. Mycobacteriology, vol. 7, no. 3, pp. 288–291, 2018, doi: 10.4103/ijmy.ijmy_65_18

[2] Kementerian Kesehatan Republik Indonesia, “Profil Kesehatan Indonesia tahun 2016,” Jakarta, 2017.

[3] F. Rosandali, R. Aziz, and N. Suharti, “Hubungan antara pembentukan Scar Vaksin BCG dan Kejadian infeksi Tuberkulosis,” J. Kesehat. Andalas Univ. Andalas, vol. 5, no. 2, pp. 381–384, 2016.

[4] C. K. Susanto, A. Wahani, and J. Rompis, “Hubungan pemberian imunisasi BCG dengan kejadian TB paru pada anak di Puskesmas Tuminting periode Januari 2012 – Juni 2012,” e-CliniC, vol. 4, no. 1, 2016, doi: 10.35790/ecl.4.1.2016.11691.

[5] Kementerian Kesehatan Republik Indonesia, “Pedoman Nasional Pengendalian Tuberkulosis Tahun 2014,” Jakarta, 2015.

[6] Situbondo Public Health Center, ”TB Program Data Report at Situbondo regency,” Situbondo, 2018.

[7] Wonorejo Public Health Center, “TB Program Data Report at Wonorejo,” Wonorejo, 2019.

[8] F. A. W. Verreck et al., “Variable BCG efficacy in rhesus populations: Pulmonary BCG provides protection where standard intra-dermal vaccination fails,” Tuberculosis, vol. 104, pp. 46–57, 2017, doi: 10.1016/

[9] E. B. Hurlock, Perkembangan Anak Jilid II. Jakarta: Erlangga, 1999.

[10] Yulistyaningrum and D. S. S. Rejeki, “Hubungan Riwayat Kontak Penderita Tuberkulosis Paru (TB) dengan Kejadian TB Paru Anak di Balai Pengobatan Penyakit Paru-Paru (BP4) Purwokerto,” Jurnal KES MAS UAD, vol. 4, no. 1, 2010.

[11] G. Briassoulis et al., “Early enteral administration of immunonutrition in critically ill children: results of a blinded randomized controlled clinical trial,” Nutrition, vol. 21, no. 7-8, pp. 799-807, 2005, doi: 10.1016/j.nut.2004.12.006.

[12] R. D. A. Rachim, “Hubungan Pemberian Imunisasi Bcg Dengan Kejadian Tuberkulosis Pada Anak Di Puskesmas Pandian Kabupaten Sumenep,” Saintika Med., vol. 10, no. 2, p. 109, 2017, doi: 10.22219/sm.v10i2.4158.

[13] M. Said and Boediman, Buku Ajar Respirologi Anak. Jakarta: IDAI, 2008.